Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Vol. 7 No. 2 (2025)

Formulation and Antioxidant Evaluation of Clay Masks Containing Robusta Coffee Pulp Extract

Fith Khaira Nursal (Department of Pharmaceutics, Magister of Pharmaceutical Science, School of Postgraduate, Universitas Muhammadiyah Prof. DR. HAMKA Jl. Warung Buncit Raya No.17, Jakarta Selatan, Indonesia, 12740)
Anisa Amalia (Department of Pharmaceutis, Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460)
Karsiti Karsiti (Pharmacy Study Programe, Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460)
Sri Nevi Gantini (.Pharmacy Study Programe, Faculty of Pharmacy and Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jl. Delima II/IV, Jakarta Timur, Indonesia 13460)



Article Info

Publish Date
31 Dec 2025

Abstract

The pulp of robusta coffee (Coffea canephora L.) is known to contain chlorogenic acid compounds that have potential as antioxidants. The content of this compound can be utilized as an active ingredient in cosmetics such as clay masks. The main component that affects the physical properties of a clay mask is the clay base. This study aims to develop a clay mask formulation from robusta coffee pulp extract with variations in the concentration of base combinations, namely bentonite and kaolin, and to observe their effects on the physical properties of the dosage form. The base concentration variations used were 20% (F1), 25% (F2), and 30% (F3) with a bentonite to kaolin ratio of 1:2. The evaluation of physical properties included organoleptic tests, homogeneity tests, pH tests, spreadability tests, adhesion tests, viscosity tests, and drying time measurements. The evaluation results showed that all clay masks were homogeneous with pH values ranging from 5.15 ± 0.04 to 5.29 ± 0.12, spreadability values of 4.60 ± 0.22 to 4.74 ± 0.37 cm, adhesion values of 0.82 ± 0.11 to 1.16 ± 0.15 seconds, and viscosity ranged from 5501 ± 670.22 to 7567.67 ± 220.30 mPa.s, and drying time ranged from 20.60 ± 0.39 to 25.34 ± 0.80 minutes. Results of the antioxidant activity test indicated that the clay mask made from robusta coffee pulp extract is a powerful antioxidant with IC50 values of 28.31 ± 4.72 to 30.45 ± 5.69 ppm. Variations in the concentration of the clay mask base significantly (p < 0.05) affected the viscosity and drying time of the dosage form. In summary, the clay mask formulations satisfied the essential physical criteria and showed promise for cosmetic application. F3 emerged as the leading formula, exhibiting the highest antioxidant capacity, evidenced by its lowest IC₅₀ value.

Copyrights © 2025






Journal Info

Abbrev

pbsj

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Description

Pharmaceutical and Biomedical Sciences Journal is an official peer-reviewed, open access journal that is managed by the Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia. This journal publishes original research articles, review articles, as well as short ...