Acne vulgaris is a chronic inflammatory skin disease that often occurs in adolescents and youngadults and is thought to be influenced by academic stress, especially in medical students. This study aims to determine the relationship between academic stress levels and the severity of Acne vulgaris in students of the Faculty of Medicine, Muhammadiyah University of Palembang. The study used a cross-sectional design through total sampling. The level of academic stress was measured using the Perceived Academic Stress Scale (PASS) questionnaire and the severity of Acne vulgaris was assessed based on the Lehmann classification. Data analysis used the Spearman Rho correlation test (α = 0.05). The results showed that the majority of respondents experienced moderate academic stress (64.2%) and severe Acne vulgaris (51.4%). Bivariate analysis showed no significant relationship between academic stress and the severity of Acne vulgaris (p = 0.392).
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