Jurnal Biomedika dan Kesehatan
Vol 9 No 1 (2026)

Diagnostic Role of the Stiff Rim Sign in Shear Wave Elastography For Guiding Biopsy Recommendation for BI-RADS 3 and 4 Breast Lesions: A Systematic Review

Astien, Astien (Unknown)
Al Azizah, Fauziyyah Nuur (Unknown)
Ranika, Meita (Unknown)



Article Info

Publish Date
31 Mar 2026

Abstract

Breast ultrasound is commonly used to evaluate breast lesions, but distinguishing benign from malignant masses remains challenging, particularly in BI-RADS category 3 and 4 lesions. Shear wave elastography measures tissue stiffness and may improve diagnostic accuracy. One important feature is the stiff rim sign, which indicates increased stiffness around a lesion. This systematic review evaluated the diagnostic role of the stiff rim sign in breast lesions. A literature search was conducted for studies assessing shear wave elastography in ultrasound-detected breast lesions. Six studies met the inclusion criteria. The results consistently showed that the stiff rim sign had moderate to high accuracy in differentiating malignant from benign lesions. Peri-lesional stiffness was strongly associated with malignant pathology and improved diagnostic performance when combined with conventional ultrasound. Overall, the stiff rim sign may help improve risk assessment and support biopsy decision-making in BI-RADS 3 and 4 breast lesions. Keywords: stiff rim sign; shear wave elastography; breast lesion; BI-RADS; breast cancer diagnosis; biopsy.

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Journal Info

Abbrev

jbk

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Jurnal Biomedika dan Kesehatan is an official publication of Faculty of Medicine Trisakti University. Jurnal Biomedika dan Kesehatan is a third-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Jurnal ...