Artificial Intelligence (AI)-based Decision Support Systems (DSS) have become a central component of digital transformation initiatives across various industries. While prior studies have primarily emphasized technical aspects such as accuracy, performance, and computational efficiency, less attention has been given to the integration of human-centered principles and scalable architectural design. This study aims to examine how AI-based DSS can be enhanced through the combined application of Human-Centered Artificial Intelligence (HCAI) principles and scalable AI architecture. Using a qualitative, literature-based research methodology, this study systematically analyzes peer-reviewed publications indexed in Scopus to identify key dimensions influencing the effectiveness and sustainability of AI-driven DSS. The findings indicate that technical capabilities alone are insufficient to ensure successful adoption and long term impact. Instead, transparency, explainability, ethical governance, and user empowerment core elements of HCAI are critical for fostering trust and user acceptance. Furthermore, scalable architectural principles, including modularity, interoperability, and adaptability, are essential for enabling AI-based DSS to operate reliably in large-scale and dynamic environments. This study contributes a unified conceptual framework that bridges technical scalability and human-centered design, offering theoretical insights and practical guidance for developing trustworthy, scalable, and sustainable AI-based Decision Support Systems in digital transformation contexts.
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