Volatility in the pharmaceutical industry can be caused by expiration of drug patents, leading to a gap between actual and target sales values, which necessitates accurate sales forecasting for pharmaceutical marketers. This study utilizes the sales data from PT. Q, an Indonesian pharmaceutical firm. The comparative performance within the specific context of the post-patent period for pharmaceutical sales remains relatively unexplored. This research aims to compare forecasting models for post-patent pharmaceutical sales. The research method utilized is based on the CRISP-DM data mining framework. The forecasting process is done on a 4.5-year timeframe using forecasting models such as ARIMA, SARIMA, LSTM, and Prophet. The results show that multivariate LSTM works better for forecasting in smaller aggregations in the dataset such as by product type and branch, with a R² score value of up to 0.64 in the aggregation level of Bandung_Sales, and with the smallest error metric values, such as MAE in many aggregation levels, example being regional sales, such as Lampung_Sales with 1.31 and Makassar_Sales with 0.26, which outperforms the other compared models in the majority of cases. This research concludes that multivariate LSTM is a better way to replace outdated methods to set sales targets.
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