This study aims to analyze the mediation of job satisfaction on the relationship between Islamic work ethics and Islamic organizational culture with employee performance, the population in this study were all employees of Bank Tabungan Negara Syariah Branch Office Serang as many as 100 employees who served as respondents. The data used in this study are primary data, obtained through questionnaires sent to 100 respondents. The data were processed using the SmartPLS 3.2.9 application, and analyzed using the Structural Equation Modeling Partial least Square (SEM-PLS) technique. The results of this study indicate that Islamic work ethics directly have a negative and insignificant effect on the performance of employees of Bank BTN Syariah Branch Serang, while Islamic organizational culture directly has a significant positive effect on employee performance, Islamic work ethics and Islamic organizational culture also have a significant positive effect on employee job satisfaction, and each of the variables of Islamic work ethics and Islamic organizational culture indirectly have a significant positive effect on the performance of employees of Bank BTN Syariah Branch Serang through the mediation of job satisfaction..
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