Analysis of Risk Factors for The Severity of Hyaline Membrane Disease in Preterm Infants Based on Modality Chest X-Ray

Aulia Kusuma Dewi (Faculty of Medicine Diponegoro University Semarang)
Farah Hendara Ningrum (Department Radiology, Faculty of Medicine Diponegoro University /Kariadi Hospital Semarang)
Adhie Nur Radityo Suswihardhyono (Department Pediatric Faculty of Medicine Diponegoro University /Kariadi Hospital Semarang)
Lydia Widyastuti Setjadiningrat Kuntjoro (Department Radiology, Faculty of Medicine Diponegoro University /Kariadi Hospital Semarang)

Medica Hospitalia
Vol. 12 No. 1 (2025): Med Hosp

BACKGROUND : Hyaline membrane disease is one of the leading causes of morbidity and mortality in premature infants. Chest X-ray examination can significantly improve the diagnosis of hyaline membrane disease. AIMS :  This study aims to examine the relationship between risk factors and the severity of hyaline membrane disease using chest X-ray modalities. METHOD : An analytic observational study with a cross sectional and  retrospective approach was conducted. Consecutive sampling of 30 preterm infants’s medical records and thoracic X-ray at Dr. Kariadi Hospital Semarang was used. Data collection was carried out from April to July 2023. Statistical tests included the Contingency Coefficient Correlation Test and  Intraclass Correlation Coefficient (ICC). RESULT :  Findings indicate that HMD severity is associated with lower birth weights (p = 0.020; r = 0.392); gestational ages (p = 0.011; r = 0.420) and maternal hypertension (p = 0.013; r = 0.414). Preeclampsia, delivery method, and gender not significantly related to the HMD severity (p>0.05). CONCLUSION : Infant birth weight, gestational age, and maternal hypertension are significantly associated with the severity of hyalin membrane disease.