Hepatitis C virus is a major health problem because of its effect on the liver and health and its being life-threatening if not treated early. It also affects the blood parameters of those infected. The current study conducted in Thi-Qar province revealed changes in some blood parameters of the infected group compared to the control group, where a slight decrease was recorded in WBCs, RBCs, PCV, MCV, MCH, PLT, Lymp. but no significant differences were found, except for red blood cells, which were 0.03 at a significant level 0.05. It was also found that the highest infection rate was in the age group of 30-39 years, while no infection was recorded in the age group of 50-59 years. Highlights: Hepatitis C impacts liver health and alters blood parameters. Significant RBC change noted; highest infection in 30β39 age group. No infections in the 50β59 age group recorded. Keywords: HCV, Hematological, ELISA, Thi-Qar
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