Kwaghe International Journal of Sciences and Technology
Vol 1 No 1 (2024): Kwaghe International Journal of Sciences and Technology

Mathematical Model for Prevention and Control of Cholera Disease in Nigeria

Okorie Charity Ebelechukwu (Unknown)
Zando Asim Abraham (Unknown)
Ochigbo Josephine E (Unknown)



Article Info

Publish Date
19 Jul 2024

Abstract

In this research work, we modified an existing mathematical model that can accommodate the gaps we discovered from the existing model. The modification centered on addition of a compartment called Isolation compartment into the existing model. The isolation is added as part of the control measures. This is one of the factors that make eradication of cholera impossible. We checked for the existence and uniqueness of the modified model and observed that the modified equations are unique and they exist. Maple 2023 and R studio software were used in carrying out the analysis. The disease-free equilibrium (DFE) state of the model was determined and used to compute the basic reproduction number R0, as a threshold for effective disease management. The results from stability analysis for the disease-free equilibrium (DFEs) shows that it is locally asymptotically stable whenever the basic reproduction number is less than unity (R0< 1). The result obtained from sensitivity index of R0 shows that the control parameters (isolation) of susceptible individual is crucial parameter to cholera management. It is recommended that isolation and awareness should be given prompt response as strategies in eradicating cholera disease so as to avoid prolonged illness and death.

Copyrights © 2024






Journal Info

Abbrev

KIJST

Publisher

Subject

Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Environmental Science Law, Crime, Criminology & Criminal Justice Social Sciences

Description

Kwaghe International Journal of Sciences and Technology aims to publish rigorous, peer-reviewed scholarship that advances natural sciences, agriculture, and technology through high-quality quantitative, qualitative, and mixed-methods research. The journal prioritizes methodological transparency, ...