This study aims to analyze the relationship between Management Information Systems (MIS) and digital organizational culture in supporting organizational transformation in the digital era. The approach used was quantitative with an associative research design. Data were collected through questionnaires distributed to 80 respondents who were active employees using MIS, using a purposive sampling technique. The research instrument used a Likert scale and had undergone validity and reliability tests. Data analysis was performed using descriptive statistics, Pearson correlation, and simple linear regression with the help of IBM SPSS Statistics software. The results showed that the level of implementation of MIS and digital organizational culture was in the high category. The correlation test showed a strong and significant relationship between MIS and digital organizational culture with a correlation coefficient of 0.68. The results of the regression test showed that MIS had a positive and significant effect on digital organizational culture with a coefficient of determination of 46%. These findings indicate that the success of MIS implementation is not only determined by technological aspects, but also greatly influenced by an organizational culture that is adaptive to digital change. Therefore, organizations need to integrate information system development with the formation of a strong digital culture to improve performance and competitiveness.
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