<![CDATA[This study aims to analyze the effect of Management Information Systems (MIS) on the effectiveness of decision-making in modern organizations. The approach used is quantitative with an explanatory research design. Data were collected through questionnaires distributed to 100 respondents, consisting of employees and managers who utilize Management Information Systems in their work activities. The data analysis technique employed is linear regression to examine the relationship between variables. The results show that Management Information Systems have a positive and significant effect on decision-making effectiveness, with a coefficient value of 0.65 and a significance level of 0.000. The coefficient of determination (R²) of 0.58 indicates that MIS explains 58% of the variation in decision-making effectiveness. This suggests that system quality, information quality, and ease of use play important roles in improving the speed, accuracy, and relevance of decisions. In conclusion, Management Information Systems have a strategic role in supporting effective decision-making in modern organizations. Therefore, organizations are advised to optimize the implementation of MIS and enhance human resource competencies to maximize the benefits of the system used.]]>
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