<![CDATA[Exposure to cigarette smoke during pregnancy may impair maternal oxygenation and affect fetal well-being, particularly in areas with a high prevalence of smoking such as Jambi, Indonesia. This study aimed to assess differences in maternal oxygen saturation and fetal heart rate among pregnant women in the second and third trimesters based on exposure to cigarette smoke. An observational analytic study with a cross-sectional design was conducted involving 45 pregnant women attending antenatal care at Rawasari Public Health Center, Jambi City, in 2024. Exposure to cigarette smoke was assessed using questionnaire, maternal oxygen saturation was measured using a pulse oximeter, and fetal heart rate was measured using a Doppler device. Data were analyzed using the Mann–Whitney test. The results showed that most pregnant women had normal oxygen saturation levels, with no statistically significant difference between those exposed and not exposed to cigarette smoke (p = 0.282). In contrast, fetal heart rate was significantly higher in the group exposed to cigarette smoke compared to the unexposed group (p = 0.002). This indicates that there was no significant difference in oxygen saturation in pregnant women based on exposure to cigarette smoke, but there was a significant difference in fetal heart rate between pregnant women who were exposed and those who were not exposed to cigarette smoke.]]>
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