<![CDATA[Hypertension is a progressive cardiovascular disease with a rising global prevalence. While patient adherence is a critical determinant of therapeutic success, maintaining consistent compliance remains a significant challenge in primary healthcare. Objective: This study aims to analyze the influence of Drug Information Services (DIS) on the medication compliance levels of hypertension patients at the Paleleh Barat District Health Center. Methods: A quantitative descriptive study with a correlational design was conducted involving 174 hypertensive patients selected through purposeful sampling. Data were collected using validated structured questionnaires. Statistical analysis was performed using univariate and bivariate methods, specifically simple linear regression. Results: Descriptive analysis revealed that DIS was predominantly rated as "Good" (98.9%), and patient compliance was largely categorized as "High" (75.9%). However, the linear regression analysis yielded a significance value of p = 0.440 (p > 0.05). Conclusion: The findings indicate that Drug Information Services do not have a statistically significant direct effect on medication compliance at this facility. The lack of statistical significance is likely attributed to data homogeneity and the 'ceiling effect,' suggesting that adherence in this rural context is driven by external factors such as family support and intrinsic patient motivation.]]>
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