Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)
Vol. 23 No. 1 (2026): Jurnal Ilmu Farmasi dan Farmasi Klinis (JIFFK)

Effectiveness of Solid Antibacterial Soap Formulated with Green Mussel Shell Waste (Perna viridis) against Staphylococcus aureus

Muyassar, Belvan Adzin Muyassar (Unknown)
Santoso, Joko (Unknown)
Sasmito, Ediati (Unknown)



Article Info

Publish Date
01 May 2026

Abstract

Staphylococcus aureus is a major cause of skin infections and remains a public health concern due to its high prevalence and the increasing emergence of antibiotic-resistant strains such as methicillin-resistant S. aureus (MRSA). These conditions highlight the importance of preventive approaches using non-antibiotic topical products. This study aimed to evaluate the antibacterial effectiveness of solid soap formulated with green mussel shell powder (Perna viridis), as well as its physical quality and consumer acceptance. A true experimental posttest-only control group design was applied using five formulations: F I (2%), F II (4%), F III (6%), F IV (0%, negative control), and F V (benzalkonium chloride as positive control). Antibacterial activity was assessed using the disc diffusion method, and the data were analyzed using one-way ANOVA. The results showed a concentration-dependent antibacterial effect, with higher concentrations of green mussel shell powder producing greater inhibition against S. aureus. All formulations met physical quality standards and demonstrated good stability and homogeneity. Sensory evaluation indicated high consumer acceptance across all formulations. Overall, these findings suggest that green mussel shell powder has strong potential as a sustainable and effective antibacterial ingredient for solid soap formulations intended for preventive skin hygiene

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Journal Info

Abbrev

Farmasi

Publisher

Subject

Medicine & Pharmacology

Description

Selamat datang di situs e-Publikasi Ilmiah Fakultas Farmasi Unwahas (Universitas Wahid Hasyim) Semarang. Situs ini berisi kumpulan publikasi ilmiah yang diterbitkan oleh Fakultas Farmasi Unwahas. Publikasi berasal dari jurnal-jurnal serta hasil prosiding seminar yang dilaksanakan oleh Fakultas ...