Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)
Vol. 23 No. 1 (2026): Jurnal Ilmu Farmasi dan Farmasi Klinis (JIFFK)

Antioxidant Potential of Garlic (Allium sativum) Ethanol Extract in Gel Formulation Assessed by DPPH Method

novita, dian (Unknown)



Article Info

Publish Date
01 May 2026

Abstract

Garlic (Allium sativum) is known to have antioxidant activity that is beneficial to health. Antioxidant activity is expressed in IC₅₀ value, which is the concentration of the extract that can reduce 50% of free radicals. This study aims to test the antioxidant activity of a gel formulated from garlic extract using the DPPH (2,2-diphenyl-1-pyrrylhydrazine) method. The garlic extract and garlic gel extract were tested to evaluate the % inhibition and IC₅₀ values. Garlic ethanol extract showed an IC50 value of 89,290, and garlic ethanol extract gel showed the % inhibition value of 87,30. The decrease in the IC₅₀ value indicates that the gel formulation provides significant antioxidant activity against DPPH free radicals. In conclusion, the ethanol extract of Allium sativum formulated into a gel showed antioxidant activity based on IC₅₀ and percentage of inhibition values obtained from the DPPH assay.

Copyrights © 2026






Journal Info

Abbrev

Farmasi

Publisher

Subject

Medicine & Pharmacology

Description

Selamat datang di situs e-Publikasi Ilmiah Fakultas Farmasi Unwahas (Universitas Wahid Hasyim) Semarang. Situs ini berisi kumpulan publikasi ilmiah yang diterbitkan oleh Fakultas Farmasi Unwahas. Publikasi berasal dari jurnal-jurnal serta hasil prosiding seminar yang dilaksanakan oleh Fakultas ...