<![CDATA[Background: Septic shock is a life-threatening condition characterized by cardiovascular dysfunction, which can cause multi-organ failure and high mortality rates. Central venous oxygen saturation (ScVO2), PCO2 Gap, and respiratory quotient are potential markers of tissue perfusion and oxygenation, while cardiac output is an important indicator of cardiovascular function. These findings may help guide clinical management and prognosis assessment in patients with septic shock.Objective: To determine the correlation between ScVO2, PCO2 Gap (arterial-venous PCO2 gradient), and respiratory quotient on cardiac output in septic shock patients.Methods: This observational study was conducted on 30 septic shock patients treated in the intensive care unit (ICU). Blood samples were taken via central venous catheter (CVC) and arterial line to check central venous saturation (ScVO2), PCO2 Gap, and calculate the respiratory quotient. Then cardiac output is measured using echohemodynamics.Results: Based on analysis using the Spearman Rho test, the results show that the correlation between ScVO2 and cardiac output has a correlation value of -0.367 (p = 0.046). The correlation between PCO2 Gap and cardiac output has a correlation value of -0.520 (p=0.003). The correlation between respiratory quotient and cardiac output in this study had a correlation value of -0.833 (p < 0.001).Conclusion: There is a correlation between ScVO2, PCO2 Gap (arterial-venous PCO2 gradient), and respiratory quotient on cardiac output in septic shock patients.]]>
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