Background: Migraine is a common neurological disorder that significantly affects quality of life and daily functioning. Despite this, the existing evidence remains inconsistent and requires further clarification through comprehensive analysis. The aim of this study was to analyze and estimate the effectiveness of acupuncture in reducing migraine pain score and medication use. Methods: This is a systematic review and meta-analysis of twelve Randomized Control Trial studies. The data used for this study sourced from following database: PubMed, ScienceDirect, and Google Scholar between 2015-2024. The data selection was carried out using PRISMA flowchart. The statistical analysis was conducted with Review Manager 5.4.1. Effect sizes were pooled using a random-effects model to account for heterogeneity across studies. Results: Result of meta-analysis showed that acupuncture can reduce migraine pain intensity (SMD= -1.05; 95% CI= -1.73 to -0.37; p=0.002) and medication use (SMD= -1.61; 95% CI= -2.99 to -0.23; p=0.02). Conclusion: Acupuncture is effective in reducing both migraine pain intensity and medication use, indicating its potential as a non-pharmacological treatment option for migraine management. Acupuncture may be considered as an adjunct therapy in clinical practice for migraine patients, and further high-quality randomized controlled trials are recommended to strengthen the evidence base.
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