Effective treatment of lung cancer depends on early and accurate detection, which continues to be a major cause of cancer-related fatalities globally. Conventional diagnostic techniques are useful, but their efficacy in handling large amounts of thoracic computed tomography (CT) scan data is limited by their time-consuming nature and susceptibility to human error. The research here suggests a new deep learning model that integrates generative adversarial networks (GANs) for data improvement with a sophisticated ensemble approach to classification. GANs are employed to generate realistic synthetic CT images, addressing the challenges of limited datasets. The backbone of the proposed approach is a consensus-guided adaptive blending (CGAB) ensemble model that learns to dynamically combine the predictions of three top-performing convolutional neural networks (CNNs): ResNet-152, DenseNet-169, and EfficientNet-B7. The CGAB model improves prediction accuracy through model contribution weighting based on confidence scores and inter-model consensus, while a conflict-resolving auxiliary decision model is used. The approach was tested using the lung image database consortium and the image database resource initiative (LIDC-IDRI) dataset with a detection rate of 97.35%, surpassing single model and traditional ensemble methods. The current work provides a solid and scalable approach to lung cancer detection with better generalization, increased diagnostic consistency, and applicability for clinical use.
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