Jurnal Anestesiologi Indonesia
Publication In-Press

Comparison Between Ketamine and Paracetamol in The Prevention of Post-Spinal Anesthesia Shivering in Caesarean Section Procedures

Candra Ristiana (Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Diponegoro/Dr. Kariadi General Hospital, Semarang|Universitas Diponegoro/Dr. Kariadi General Hospital, Semarang)
Himawan Sasongko (Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Diponegoro/Dr. Kariadi General Hospital, Semarang|Universitas Diponegoro/Dr. Kariadi General Hospital, Semarang)
Yulia Wahyu Villyastuti (Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Diponegoro/Dr. Kariadi General Hospital, Semarang|Universitas Diponegoro/Dr. Kariadi General Hospital, Semarang)



Article Info

Publish Date
25 Oct 2021

Abstract

Background: Shivering is a common complication associated with spinal anesthesia during cesarean sections, leading to discomfort and potential cardiac ischemia. While intravenous paracetamol is known to prevent shivering, it has potential peripheral limitations and may be costly. Conversely, ketamine administration inhibits norepinephrine reuptake, potentially reducing heat redistribution and serving as a more affordable alternative.Objective: Assessing the comparison of ketamine and paracetamol on the incidence, onset, and degree of post-spinal anaesthesia shivering in caesarean section procedures.Methods: An experimental design was employed with a sample size of 52 patients, divided into two groups: one receiving intravenous ketamine (0.25 mg/kg) alongside intrathecal bupivacaine (15 mg), and the other receiving intravenous paracetamol (1000 mg) with intrathecal bupivacaine (15 mg). The incidence, onset, and degree of shivering were observed and recorded every 3 minutes for 90 minutes.Results: The incidence of shivering in the ketamine group was 3 samples while in the paracetamol group there were 10 samples. The mean time of onset of shivering in the ketamine group was 55.00 minutes, and in the paracetamol group was 27.30 minutes (p<0.05). While the degree of shivering in the ketamine group was 1 sample of degree 1 and 2 samples of degree 2, the paracetamol group was 4 samples of degree 2, 3 samples of degree 3 and 3 samples of degree 4 (p<0.05).Conclusion: Ketamine proved to be more effective in preventing shivering than paracetamol after spinal anesthesia in caesarean section procedures.

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Journal Info

Abbrev

JAI

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Anestesiologi Indonesia (JAI) diterbitkan oleh Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) dan dikelola oleh Program Studi Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Diponegoro (UNDIP) bekerjasama dengan Perhimpunan Dokter Spesialis ...