Acute Respiratory Infection (ARI) is an acute infectious disease affecting one or more parts of the respiratory tract, ranging from the nose to the alveoli, including its adnexal tissues. Several factors influencing the incidence of ARI among employees include age, smoking habits, use of personal protective equipment (PPE) masks, temperature, humidity, and family history of ARI. This study aimed to determine the association between age, smoking habits, PPE mask use, temperature, humidity, and family history of ARI with the incidence of ARI among employees at Tanjung Priok Regional General Hospital in 2025. This research employed a quantitative approach using a cross-sectional study design. The study population consisted of all employees at Tanjung Priok Regional General Hospital, totaling 252 individuals. The sample size was determined using a two-proportion hypothesis test formula, resulting in 96 respondents. Stratified random sampling was applied as the sampling technique. Data processing and analysis were conducted using the Chi-Square test. The results showed a significant association between family history of ARI (p = 0.005) and the incidence of ARI among employees. Meanwhile, there were no significant associations between age (p = 0.346), smoking habits (p = 0.768), PPE mask use (p = 0.387), temperature (p = 0.329), and humidity (p = 0.942) with the incidence of ARI among employees at Tanjung Priok Regional General Hospital.
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