Effective inventory management is a determining factor in the probability and sustainability of micro, small, and medium enterprises (MSMEs). Adjusting the ideal stock of each product type that has to be distributed while taking perishable items, storage capacity constraints, and client demand unpredictability into account is a difficulty. Stock allocation must maximize profit while adhering to intricate constraints and particular item number limitations in the multiple-constraints Knapsack problem. This research aims to apply the Grey Wolf Optimizer (GWO) algorithm to the multiple constraints bounded Knapsack problem for optimal stock allocation while increasing profitability for MSMEs by comparing the ideal value of the simplex technique. The population parameter (Npop) and the maximum iteration (Max Iter) were the two parameters used to test the GWO method. According to sensitivity analysis, the GWO algorithm optimization study was less successful in producing the best outcomes. This resulted from a discrepancy between the simplex method's IDR 9,508,000 profit optimization and GWO's IDR 9,440,000. Nonetheless, the GWO method was almost ideal, as indicated by the deviation percentage of 0.7152%. The study highlights the applicability of metaheuristic optimization for MSME management inventory, offering a near-optimal solution with minimal deviation from analytical results. Limitations include the single-case scope and parameter sensitivity of the GWO algorithm.
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