Improving rice productivity requires proper crop management practices, including effective disease control. The objective of this study is to analyze the potential application of Score 250 EC®, with the active ingredient difenoconazole, for the growth of the IR 64 rice variety (Oryza sativa). The experiment was conducted using a Randomized Block Design (RBD) with seven concentration levels, namely S0 = 0 L (control), S1 = 0.075 L, S2 = 0.150 L, S3 = 0.225 L, S4 = 0.300 L, S5 = 0.375 L, and S6 = 0.450 L, where each concentration was diluted in 500 L of water per hectare (ha⁻¹). The 1,000-grain weight parameter showed a significant effect across treatments compared to the control. The treatment with a concentration of 0.300 L Score per 500 L water ha⁻¹ resulted in the highest average weight of 24.78 g. Meanwhile, for the milled dry grain parameter, the concentration of 0.300 L Score per 500 L water ha⁻¹ produced the highest average yield of 7.21 t ha⁻¹
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