Leprosy is a chronic infectious disease that requires high adherence to multidrug therapy (MDT) to prevent further complications and transmission. However, the level of patient compliance in undergoing treatment is still a challenge, especially in areas with limited access such as Sarmi Regency, Papua Province. This study aims to analyze the determinants of leprosy treatment adherence based on Lawrence Green's theory, which includes predisposition, enabling, and reinforcing factors. This study uses a quantitative method with the Partial Least Squares - Structural Equation Modeling (PLS-SEM) approach. Data was collected through a questionnaire given to 100 respondents with leprosy in Sarmi Regency.
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