journal of Basic Medical Veterinary
Vol. 15 No. 1 (2026): Journal of Basic Medical Veterinary, June 2026

Haematological Recovery in a Juvenile Rabbit with Severe Pancytopenia Following Ascorbic Acid Supplementation

Jee Wen Li (Division of Veterinary Basic Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Indonesia)
Michelle Tandika Hadi (Division of Veterinary Basic Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Indonesia)
Tan Ying Jie (Division of Veterinary Basic Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Indonesia)
Nur Shaqeera Farhanah Binti Rosli (Division of Veterinary Basic Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Indonesia)
Lim Chi Yao (Division of Veterinary Basic Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Indonesia)



Article Info

Publish Date
01 Jun 2026

Abstract

A 1.5-month-old domestic rabbit weighing 725 g presented with severe pancytopenia characterized by critical reductions in red blood cells (RBC: 1.00 × 10⁶/µL), white blood cells (WBC: 0.7 × 10³/µL), haemoglobin (1.7 g/dL), haematocrit (6.4%), and platelets (54 × 10³/µL). The rabbit exhibited moderate stress but remained alert and responsive. Given the life-threatening haematological status and the absence of a specific underlying disease, supportive therapy with oral ascorbic acid supplementation was initiated at 100 mg/kg/day for seven days. Post-treatment haematological evaluation demonstrated a dramatic recovery, with RBC increasing to 5.71 × 10⁶/µL, WBC to 5.4 × 10³/µL, haemoglobin to 9.9 g/dL, haematocrit to 35%, and platelets to 225 × 10³/µL. A second rabbit with more severe baseline pancytopenia (RBC: 0.40 × 10⁶/µL, WBC: 0.2 × 10³/µL) receiving identical treatment died on day six, demonstrating the prognostic significance of baseline haematological severity. This case illustrates the potential role of ascorbic acid in supporting haematopoietic recovery in juvenile rabbits with reversible bone marrow suppression and highlights the importance of early intervention before critical thresholds are exceeded. Vitamin C supplementation may represent a valuable supportive therapy in young rabbits experiencing stress-related or nutritional haematological compromise.

Copyrights © 2026






Journal Info

Abbrev

JBMV

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Description

This journal published original articles, review articles, and case studies in Indonesian or English, in the scope of JBMV has a broad coverage of relevant topics across veterinary basic medical sciences which includes: preclinical and paraclinical disciplines like Anatomy, Physiology, Biochemistry, ...