<![CDATA[This research seeks to evaluate and contrast the effectiveness of two deep learning models, Xception and ConvMixer, for classification of skin disease images. An experimental methodology was employed using the Massive Skin Disease. The data is divided into training, validation, and test data with a ratio of 80:10:10. The pre-processing stage includes resizing, normalization, and the application of geometric augmentation to improve visual variation in the training data. Both models were trained using equalized parameters so that comparisons were made objectively. The models were assessed through several evaluation metrics, including loss, accuracy, precision, recall, and F1-score metrics in a multi-class classification scheme. The results showed that Xception obtained a test accuracy of 99,70%, while ConvMixer achieved 94,60%. Additionally, Xception exhibits faster convergence and more stable inter-class performance consistency, while ConvMixer excels in compute time efficiency. This study contributes in the form of a comparative analysis of two modern architectures with training parameters that are equalized in the classification of skin diseases. However, the study is still limited to the use of a partial class and a single dataset, so further testing is needed to ensure the generalization capabilities of the model over a wider range of scenarios.]]>
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