Jurnal Anestesiologi Indonesia
Publication In-Press

Comparison of the Effects of Continuous Infusion of Fentanyl 0.7 mcg/kgBW/hour versus Lidocaine 1.5 mg/kgBW/hour on Post-Anesthesia Recovery Quality Using QoR-40 Scoring in Laparotomy Surgery

Sherwin Sherwin (Faculty of Medicine, Universitas Sumatera Utara/Adam Malik Hospital, Medan|Universitas Sumatera Utara/Adam Malik Hospital, Medan)
Rr Sinta Irina (Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara/Adam Malik Hospital, Medan|Universitas Sumatera Utara/Adam Malik Hospital, Medan)
Andriamuri Primaputra Lubis (Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara/Adam Malik Hospital, Medan|Universitas Sumatera Utara/Adam Malik Hospital, Medan)



Article Info

Publish Date
25 Oct 2021

Abstract

Background: Postoperative recovery quality is a critical measure of anesthetic effectiveness, particularly in major surgeries such as laparotomy. Both fentanyl and lidocaine are used in multimodal analgesia, but their comparative efficacy on recovery quality remains underexplored.Objectives: To evaluate and compare the impact of continuous intravenous infusions of fentanyl as well as lidocaine on the quality of postoperative recovery in laparotomy patients undergoing general anesthesia, utilizing the quality of recovery-40 (QoR-40) score as the evaluation instrument.Methods: This double-blind randomized controlled trial (RCT) included 40 patients undergoing laparotomy at Adam Malik Hospital, Medan. Subjects were randomly allocated to receive either fentanyl (0.7 mcg/kg/h) or lidocaine (1.5 mg/kg/h) infusion postoperatively. QoR-40 scores were assessed 24 hours post-surgery. Pain scores and rescue analgesia requirements were also evaluated.Results: Subjects in the fentanyl group had substantially higher QoR-40 scores (173.35 ± 41.764) than those in the lidocaine group (148.95 ± 25.362; p = 0.0001). Fentanyl was superior in comfort and pain control. Rescue analgesia was needed less frequently and later in the fentanyl group (p = 0.0001).Conclusion: Fentanyl infusion substantially improved postoperative recovery quality more effectively than lidocaine in patients undergoing laparotomy, particularly in pain management and comfort.

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Journal Info

Abbrev

JAI

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Jurnal Anestesiologi Indonesia (JAI) diterbitkan oleh Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) dan dikelola oleh Program Studi Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Diponegoro (UNDIP) bekerjasama dengan Perhimpunan Dokter Spesialis ...