Media of Health Research
Vol. 4 No. 2 (2026): Media of Health Research, May 2026

Effectiveness of Digital Health Interventions on Clinical and Behavioral Outcomes in Hypertension Patients: A Systematic Review

Truly Anggraini (Doctoral Program, Faculty of Pharmacy, Universitas Muhammadiyah Surakarta, Indonesia)
Hidayah Karuniawati (Faculty of Pharmacy, Universitas Muhammadiyah Surakarta, Indonesia)
Syed Azhar Syed Sulaiman (School of Pharmaceutical Science, Universiti Sains Malaysia, Penang, Malaysia)



Article Info

Publish Date
28 May 2026

Abstract

Hypertension is a major risk factor for cardiovascular disease, yet blood pressure control remains suboptimal, especially in low- and middle-income countries. Digital health interventions (DHI) have been implemented to support hypertension management, although their effectiveness varies. This systematic review evaluated the effects of DHI on clinical and behavioral outcomes in adults with hypertension and identified the most effective type of intervention. Randomized controlled trials (RCTs) published between 2015 and 2025 were searched in PubMed, Scopus, and Google Scholar. Study selection followed the PRISMA guideline, and methodological quality was assessed using the Joanna Briggs Institute (JBI) tool. Fifteen RCTs met the inclusion criteria. Mobile-based interventions were the most frequently studied (8/15; 53.3%) and showed the most consistent benefits, including improved blood pressure control (80%), reductions in systolic (85.7%) and diastolic blood pressure (62.5%), and improvements in medication adherence (100%), self-care behavior (75%), and quality of life (100%). Telephone-based interventions (3/15; 20%) improved target blood pressure attainment and patient satisfaction, whereas web-based interventions (4/15; 26.7%) were generally less effective unless combined with telemedicine or clinical support. Overall, mobile-based DHI demonstrated the most consistent improvements in hypertension outcomes.

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Journal Info

Abbrev

mohr

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Media of Health Research (MOHR) is a national periodical journal which contains research articles in health sector. MOHR journal are expected to be a medium for conveying scientific findings and innovations in the health sector for those in the health sector, both those engaged in the health sector. ...