<![CDATA[Green tea leaves (Camellia sinensis) contain polyphenolic compounds with antioxidant potential and can be developed into topical serum preparations. This study aimed to optimize the combination of xanthan gum and carbopol in a green tea leaf ethanol extract serum using the Simplex Lattice Design method. Serum formulations were prepared using different proportions of xanthan gum and carbopol, then evaluated for viscosity, spreadability, adhesiveness, pH, organoleptic properties, and physical stability using a cycling test. The optimum formulation consisted of 55% xanthan gum and 45% carbopol, with a desirability value of 1.0. Verification showed that the predicted and observed responses were not significantly different. The optimum formula met the initial physical quality requirements; however, the cycling test showed changes in viscosity, spreadability, and adhesiveness. These findings indicate that xanthan gum and carbopol can be optimized to produce green tea extract serum, although further stability improvement is required.]]>
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