Sriwijaya Journal of Surgery
Vol. 9 No. 1 (2026): Sriwijaya Journal of Surgery

Synchronous Low-Grade Appendiceal Mucinous Neoplasm, Perforated Ascending Colon Diverticulitis, and Mature Ovarian Cystic Teratoma in a 52-Year-Old Female: Diagnostic Challenges and Surgical Decision-Making

I Made Aridana Sandika (General Practitioner, Klungkung Regional General Hospital, Semarapura, Indonesia)
Maria Yustina (Department of Digestive Surgery, Klungkung Regional General Hospital, Semarapura, Indonesia)



Article Info

Publish Date
27 May 2026

Abstract

Introduction. Low-grade appendiceal mucinous neoplasm (LAMN) is a rare mucin-producing epithelial tumor identified in roughly 0.13–1% of appendectomies, with a recognized risk of pseudomyxoma peritonei (PMP) on rupture. Synchronous coexistence with perforated ascending colon diverticulitis and an ipsilateral ovarian mature cystic teratoma is exceptional and creates a triple-layered diagnostic and operative challenge. Case Presentation. A 52-year-old Indonesian female presented with one month of right lower quadrant (RLQ) pain that worsened over forty-eight hours, accompanied by nausea and vomiting. Examination revealed McBurney tenderness, local muscular defense, and a palpable RLQ mass. Leukocytosis with neutrophilic predominance (white blood cells 19.18×10³/µL; neutrophils 91%) was noted. Ultrasonography demonstrated a lobulated, hyperechoic pelvic mass measuring 10.46 cm. Contrast-enhanced computed tomography showed a solid–cystic pelvic lesion with fat and calcification consistent with mature cystic teratoma alongside a periappendicular infiltrate. Exploratory laparotomy disclosed ~50 mL of purulent fluid, an abnormally enlarged appendix, multifocal ascending colon diverticulitis with perforation, dense adhesions, and a right ovarian mass. Right hemicolectomy with transverse colon stump and end ileostomy together with total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO) were performed. Histopathology confirmed LAMN with periappendicular infiltrate and a mature cystic teratoma of the right ovary. Conclusion. Coexistence of LAMN, perforated colonic diverticulitis, and mature ovarian teratoma can mimic adnexal or inflammatory disease and obscure recognition of the appendiceal neoplasm. Vigilant intra-operative inspection of the appendix and adjacent colon, oncologically appropriate resection, and definitive histopathology are essential to prevent PMP.

Copyrights © 2026






Journal Info

Abbrev

sjs

Publisher

Subject

Medicine & Pharmacology

Description

SRIWIJAYA JOURNAL OF SURGERY Sriwijaya Journal of Surgery (SJS) is a peer-reviewed journal published twice a year (June and December) by Department of Surgery, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia. SJS is intended to be the journal for publishing articles reporting the ...