JPSCR : Journal of Pharmaceutical Science and Clinical Research
Vol 10, No 2 (2025)

Formulation of Small Quantity Lipid-based Nutrient Supplement (SQ-LNS) Tablet from Soybean: A Preventive Approach on Stunted Birth for Pregnant and Breastfeeding Women

Siagian, Virginia Heaven Mariboto (Unknown)
Cung, Johnessa (Unknown)
Anandawijaya, Spica Diani (Unknown)
Febriliani, Sandya Amelia (Unknown)
Widyapuspita, Avika (Unknown)
Sopyan, Iyan (Unknown)



Article Info

Publish Date
24 Sep 2025

Abstract

The prevalence of stunting in Indonesia, which has not met the requirements of the WHO, makes stunting a national problem. In line with the nutritional intervention in 2020-2030, UNICEF developed SQ-LNS products as a food paste. As an effort to prevent stunting as well as improve product stability, the formulation of Small-Quantity Lipid-based Nutrient Supplements (SQ-LNS) from soybeans (Glycine max (L.) Merr) in tablet form is proposed to be a solution for pregnant and breastfeeding women. Microencapsulation technology is used to entrap soybean oil as the lipid source of this supplement. This study aims to obtain the best concentration of maltodextrin, soy protein isolate, and carboxymethyl cellulose as a soybean oil coating for felting into SQ-LNS tablet preparation. The best microcapsule is produced from a 40% formula with a percent yield of 28%, encapsulation efficiency of 79.83%, PSD microcapsule of 1.003 μm, and round agglomerated particles with a smooth surface without any residual oil seen under the SEM, and obtained the best formulation and evaluation of SQ-LNS tablets so that they meet the quality standards of good stunting supplement tablets.

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Journal Info

Abbrev

jpscr

Publisher

Subject

Environmental Science Public Health

Description

Journal of Pharmaceutical Science And Clinical Research (e-ISSN 2503-331x) offers a forum for publishing the original research articles, review articles from contributors, and the novel technology news related to pharmaceutical science and clinical research. Scientific articles dealing with natural ...