<![CDATA[Water pollution by heavy metals such as lead (Pb) causes toxic effects that inhibit the growth of aquatic organisms. Bioremediation using microorganisms such as Azotobacter sp. and Pseudomonas sp. is an environmentally friendly approach to reducing Pb toxicity through biological absorption and detoxification mechanisms. This study aimed to determine the most effective combination of biofertilizers in supporting the bioremediation process and the growth of water lettuce (Pistia stratiotes L.). The experiment was conducted in the greenhouse of the University of Singaperbangsa Karawang from January to April 2025 using a single-factor Randomized Block Design (RBD) with nine treatments and three replications. The results showed that treatment B (10 ppm Pb (50 ml Pseudomonas sp. + 25 ml Azotobacter sp.)) produced the highest values across all growth parameters. The combination of these two microorganisms enhanced nutrient availability and phytohormone production, supporting photosynthetic activity and improving the adaptation of Pistia stratiotes L. to Pb exposure, thereby demonstrating potential as an effective bioremediation agent. ]]>
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