The main focus of this research is how the epistemological construction in the thought of Muhammad Baqir Shadr? And how is the relevance of Muhammad Baqir Shadr's epistemological thought in the contemporary era? This research attempts to explain epistemology or knowledge constructively and its relationship to humans in the contemporary era. This research uses a philosophical approach that serves as a perspective in conducting research. Data is traced and collected through library research of Muhammad Baqir Shadr's works, especially those that have been translated. Then, the research data analysis method uses elements of hermeneutics, heuristics and coherence with the aim of finding conceptual clarity from related sources with the aim of finding conceptual clarity from related sources. The results of the study show that there is a very close relationship between epistemology/knowledge and human life in the contemporary era. Muhammad Baqir Shadr argues that the root of the problems of human life today is sourced from the perspective or what is commonly called worldview. The current human worldview shows many materialistic and pragmatic tendencies that are used as life goals. Muhammad Baqir Sadr emphasized the importance of a proper understanding of epistemology, which can serve as a foundation for shaping human perspectives, which is none other than Islamic epistemology. A true understanding of God, the universe, and self-existence can lead humans to the right goals and achieve true happiness.
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