This study aims to analyze the influence of biophilic architecture on psychological well-being, analyze the influence of psychological well-being on work stress, analyze the influence of biophilic architecture on work stress and examine the role of psychological well-being as a mediating variable in the relationship between biophilic architecture and teacher work stress at SMAN I Maumere. The data analysis technique used SEM PLS. The results of the analysis show that biophilic architecture has a significant influence on psychological well-being and teacher work stress at SMAN I Maumere. Psychological well-being is proven to have a negative effect on teacher work stress. Psychological well-being plays a significant mediating variable in the relationship between biophilic architecture and teacher work stress. This proves that the application of biophilic design principles not only has a direct impact on reducing stress, but also provides an indirect effect through increasing psychological well-being.
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