<![CDATA[Background: Leprosy is a chronic infectious disease that can lead to permanent disability if not properly managed, especially due to non-adherence to the Multi-Drug Therapy (MDT) regimen. Medication adherence plays a crucial role in preventing disease progression and the onset of disability. Purpose: This study aimed to examine the relationship between medication adherence and the level of disability among leprosy patients in Kunir Public Health Center, Lumajang. Methods: This research employed a quantitative, correlational design to examine the relationship between medication adherence and disability level among leprosy patients. The study population comprised all leprosy patients in Kunir Public Health Center, with a total of 14 respondents selected using total sampling. The research instruments used were the MMAS-8 questionnaire to assess adherence and the POD scale to assess disability. Data were analyzed using the Spearman Rank test with a significance level of p < 0.05. Results: Most patients had moderate medication adherence (50%), and the majority experienced Grade 1 disability (42.9%). The Spearman test revealed a significant relationship between medication adherence and disability level (p = 0.000; r = 0.930), indicating that higher adherence is associated with lower levels of disability. Conclusions: Regular and timely MDT treatment can suppress disease progression and prevent nerve damage leading to disability. Therefore, improving medication adherence should be a priority in primary healthcare-based leprosy control programs.]]>
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