This case study explores the clinical and molecular profile of male breast cancer (MBC) and underscores the diagnostic utility of immunohistochemistry. A 79-year-old man was diagnosed with grade III invasive carcinoma of no special type (NST) via histopathology and immunohistochemistry, showing ER+, PR+, HER2 3+, and Ki67 (30%) expression. The tumor was classified as Luminal B-like (HER2-positive). The findings highlight the relevance of molecular profiling in guiding treatment and prognosis in rare male breast cancer cases.
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