JFL : Jurnal Farmasi Lampung
Vol. 15 No. 1 (2026): JFL : Jurnal Farmasi Lampung

FORMULASI DAN KARAKTERISASI GEL KOMBINASI ALOE VERA DAN MENTHOL: FORMULATION AND CHARACTERIZATION OF ALOE VERA AND MENTHOL COMBINATION GEL

Yulyuswarni Yulyuswarni (Jurusan Farmasi, Poltekkes Kemenkes Tanjungkarang, Indonesia)
Ani Hartati (Jurusan Farmasi, Poltekkes Kemenkes Tanjungkarang, Indonesia)
Pudji Rahayu (Jurusan Farmasi, Poltekkes Kemenkes Tanjungkarang, Indonesia)



Article Info

Publish Date
28 Jun 2026

Abstract

Abstract Skin inflammation is a common health problem requiring effective management through safe and stable topical formulations. This study aimed to formulate and evaluate the physical characteristics of a topical gel containing a combination of Aloe vera and menthol as a potential anti-inflammatory agent. The gel was prepared using xanthan gum as the base with varying concentrations of Aloe vera powder 200x (0.25%, 0.5%, and 0.75%) and a fixed concentration of menthol (0.5%). The formulations were evaluated for organoleptic properties, homogeneity, pH, spreadability, and stability. The results showed that all formulations exhibited good physical characteristics, were homogeneous, had pH values within the physiological skin range, and demonstrated acceptable spreadability. Statistical analysis indicated that variation in Aloe vera concentration had no significant effect on pH but significantly affected spreadability. Stability testing revealed that the formulations remained relatively stable, although slight color changes occurred at elevated temperatures. These findings suggest that the Aloe vera–menthol gel has potential as a natural-based topical formulation. Keywords: Aloe vera, formulation, gel, menthol, stability

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Journal Info

Abbrev

jfl

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

Description

The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its ...