Eduvest - Journal of Universal Studies
Vol. 6 No. 3 (2026): Eduvest - Journal of Universal Studies

The Relationship Between Polyunsaturated Fatty Acid (PUFA) Intake and Cognitive Function in Psychiatric Patients with Depressive Disorders

Erlansa Budiyoga (Universitas Diponegoro)
Linda Kartikasari (Universitas Diponegoro)
Natalia Dewi Wardani (Universitas Diponegoro)



Article Info

Publish Date
19 Mar 2026

Abstract

Disturbance depressive is a mental health disorder that is often associated with cognitive decline. Nutrition, particularly polyunsaturated fatty acid (PUFA) intake, is thought to play a role in maintaining brain health and cognitive function. However, evidence of a link between PUFA intake and cognitive function as measured by the Montreal Cognitive Assessment (MoCA), Indonesian version (MoCA-Ina), in patients with depressive disorders remains limited. This study aims to evaluate the relationship between PUFA intake and cognitive function in psychiatric patients with depressive disorders. This was an analytical study using secondary data from patients with depressive disorders at Dr. Kariadi General Hospital, Diponegoro National Hospital, Banyumanik Hospital 1, and Elisabeth Hospital Semarang from May 2022 to 2023. The study included patients aged 18–60 years who were diagnosed with depressive disorders, had completed the Food Frequency Questionnaire (FFQ) and MoCA-Ina assessments, and had no serious physical illness or metabolic syndrome. The analysis used the Spearman correlation test to assess the relationship between PUFA intake and cognitive function, as well as the Mann–Whitney test for comparisons based on PUFA intake categories. A total of 30 patients with depressive disorders were included, of whom 83.3% were female, with a mean age of 26.03 years. The mean PUFA intake was 6.31 grams, and the mean MoCA-Ina score was 27.67. The Spearman test showed no significant association between PUFA intake and cognitive function (p = 0.790). There was no significant relationship between PUFA intake and cognitive function in patients with depressive disorders.

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Journal Info

Abbrev

edv

Publisher

Subject

Aerospace Engineering Computer Science & IT Health Professions Neuroscience Social Sciences

Description

Eduvest - Journal of Universal Studies is a double blind peer-reviewed academic journal and open access to multidiciplinary fields. The journal is published monthly by Green Publisher Indonesia. Eduvest - Journal of Universal Studies provides a means for sustained discussion of relevant issues that ...