Klinikal Sains (Jurnal Analis Kesehatan)
Vol. 13 No. 2 (2025): Desember

POTENSI EKSTRAK METANOL BUNGA KECOMBRANG (Etlingera elatior) SEBAGI ANTIBAKTERI TERHADAP Escherichia coli DAN Pseudomonas aeruginosa PADA PASIEN INFEKSI SALURAN KEMIH

Yusianti Silviani (Sekolah Tinggi Ilmu Kesehatan Nasional)
Sindi Noviana (SEKOLAH TINGGI ILMU KESEHATAN NASIONAL)



Article Info

Publish Date
16 Dec 2025

Abstract

Urinary tract infection is an inflammation caused by bacterial proliferation, especially Escherichia coli as the main cause and Pseudomonas aeruginosa as a nosocomial cause. Torch ginger flowers (Etlingera elatior) can be used as an alternative natural antibiotic because they contain flavonoids, saponins, tannins, alkaloids, and steroids that have antibacterial potential. This study aims to determine the effectiveness of the inhibitory power of torch ginger flower methanol extract against Escherichia coli and Pseudomonas aeruginosa bacteria that cause urinary tract infections, and to analyze whether there is a significant difference in the inhibition zone at the extract concentration with the inhibition zone in the positive control ciprofloxacin. This study used a cross-sectional experimental analytical design. Extraction was carried out by the maceration method using methanol as a solvent. Phytochemical tests were used to identify active compounds, while antibacterial tests used the Kirby-Bauer disc diffusion method. The inhibition zone was measured using a caliper and analyzed by the Shapiro-Wilk, Kruskal-Wallis, and Mann-Whitney tests. The results showed that the extract positively contained flavonoids, saponins, tannins, alkaloids, and steroids, producing an inhibitory power of 6–8 mm on Escherichia coli and 6–7 mm on Pseudomonas aeruginosa, while ciprofloxacin produced 34 mm on Pseudomonas aeruginosa and 10 mm on Escherichia coli. There was a significant difference (p ≤ 0.05) between all extract concentrations and the positive control. In conclusion, the methanol extract of torch ginger flowers has antibacterial activity, but no concentration was able to match the effectiveness of ciprofloxacin.

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Journal Info

Abbrev

klinikal

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology

Description

Jurnal klinikal sains program studi analis kesehatan adalah jurnal ilmiah yang membahas tentang kompetensi analis kesehatan yang meliputi kompetensi Mikrobiologi, Hematologi, Parasitologi, Imunoserologi, Toxikologi, dan Kimia Klinik. Jurnal klinikal sains akan terbit setiap enam bulan, dalam satu ...