This study examines the effect of integrating spiritual values into chemistry teaching materials through the Discovery Learning model on students’ learning outcomes and spiritual attitudes at SMA Negeri 5 Medan. Using a quasi-experimental design, two grade XI classes were selected, namely XI-4 (experimental) and XI-8 (control). The experimental class received spiritually integrated materials, while the control class used a standard handbook. Data were collected through learning outcomes tests and spiritual attitude questionnaires. Findings showed significant improvements in the experimental group’s post-test scores and spiritual attitudes. Statistical analysis using independent and paired sample t-tests yielded significance values of 0.000 (≤ 0.05). A Pearson correlation test showed a strong positive correlation (r = 0.644, R² = 0.414), indicating that higher spiritual attitudes are associated with better academic performance.
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