Emerging Science Journal
Vol. 10 No. 3 (2026): June

Attention-Driven Hybrid Deep Learning for Automated Alzheimer’s Disease Severity Assessment via MRI Neuroimaging

Mahimul Islam Nadim (Department of Computer Science & Engineering, Daffodil International University, Dhaka 1216)
Zahura Zaman (Department of Computing, Boise State University, Boise, ID 83725)
Md Mizanur Rahman (Department of Computer Science & Engineering, Daffodil International University, Dhaka 1216)
Abdullah Al Taky (Department of Computer Science & Engineering, Daffodil International University, Dhaka 1216)
Meherunnesa Tania (Department of Computing, Boise State University, Boise, ID 83725)
Ikteder A. Udoy (Department of Computing, Boise State University, Boise, ID 83725)
Khadiza Khanom (Department of Computer and System Science, Stockholm University, Stockholm 16407)
Md. Obaidul Islam (Department of Computer Science & Engineering, Daffodil International University, Dhaka 1216)
Suman Ahmmed (Department of Computer Science and Engineering, United International University, Dhaka 1212)
Ohidujjaman (Department of Computer Science and Engineering, United International University, Dhaka 1212)



Article Info

Publish Date
01 Jun 2026

Abstract

Early, accurate diagnosis of Alzheimer’s Disease (AD) is vital for effective intervention. Properly classifying its progression from cognitively normal to moderate dementia is essential for tailoring treatment and management plans. The proposed research is a hybrid deep learning framework that integrates the EfficientNet-B3 and the ResNet50 with sophisticated attention units in order to classify the MRI scans of Alzheimer's disease in multi-classes. The model proposed combines both a Convolutional Block Attention Module (CBAM) based on the refinement of channels and space features and Multi-Head Self-Attention based on cross-branch feature interaction. The dual-branch architecture yields complementary features, with EfficientNet-B3 being able to pick fine-grained patterns and ResNet50 being able to pick strong hierarchical representations. The characteristics in both branches are mapped to 512 dimensions, operated by multi-head attention classification. The model and extensive preprocessing were implanted on a series of 33,984 augmented Alzheimer's MRI images in four categories (MildDemented, ModerateDemented, NonDemented and VeryMildDemented. This hybrid model had outstanding performance of 98.21% test accuracy, 98.23% precision, 98.21% recall, and 98.21% F1-score, which was far much better than the accuracies of other baseline architectures such as VGG16 (74.11%), ResNet50 (93.68%), EfficientNetB0 (63.52%), DenseNet121 (64.12%), and CustomCNN (68.87%). These findings support the usefulness of hybrid systems consisting of attention mechanisms to diagnose Alzheimer's disease automatically by using neuroimaging information.

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Journal Info

Abbrev

ESJ

Publisher

Subject

Environmental Science

Description

Emerging Science Journal is not limited to a specific aspect of science and engineering but is instead devoted to a wide range of subfields in the engineering and sciences. While it encourages a broad spectrum of contribution in the engineering and sciences. Articles of interdisciplinary nature are ...