JIKA
Vol. 4 No. 2 (2026): Volume 4 Nomor 2 Juni 2026

Antioxidant Activity of Palm Kernel Oil-Vitamin C Nanoemulsion Evaluated Using the DPPH Assay Method

Muslim Suardi (Fakultas Farmasi, Universitas Abdurrab)
Yunita Amanda (Unknown)
Yan Hendrika (Unknown)



Article Info

Publish Date
01 Aug 2026

Abstract

Palm kernel oil (PKO) is an oil obtained from palm seeds (Elaeis guineensis Jacq) contains natural antioxidants. Objectives: Purposes of the study were to formulate, determine the physical characteristics of PKO nanoemulsions, and evaluate antioxidant activity. Method: The nanoemulsion was prepared into five formulations, F1, F2, F3, and F4 contained PKO at concentrations of 2, 2.5, 3, and 3.5% of PKO, respectively. F1, F2, F3, and F4 were added with vitamin C at a concentration of 2,5%. F5 as a control contained 3.5% PKO without vitamin C. Physical evaluations included organoleptic, viscosity, pH, centrifugation, transmittance, droplet size, zeta potential, and freeze-thaw tests. Antioxidant activity was evaluated using the DPPH assay method. Results: All of the physical evaluations fulfilled the requirement of nanoemulsion formulation. Antioxidant activity (IC50 value) of F1, F2, F3, F4, and F5 was 2.98 ± 0.21; 2.25 ± 0.23; 1.29 ± 0.05; 1.17 ± 0.12; and 51.96 ± 37.19 ppm, respectively. It was indicated very strong antioxidant activity, while for F5 (PKO without vitamin C) has strong activity (IC50 of 51.9 ppm). Conclusions: It is concluded that the PKO can be used as a antioxidant. PKO-Vitamin C can be formulated as a stable nanoemulsion.

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Journal Info

Abbrev

jika

Publisher

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Description

JIKA (Jurnal Ilmu Kesehatan Abdurrab) has been published since March 2023 by the Abdurrab University Research and Community Service Institute in Pekanbaru. It is released four times a year: in March, June, September, and December. This journal focuses on the fields of nursing, midwifery, medicine, ...