MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation
Vol. 7 No. 2 (2026): June

ANTIBACTERIAL ACTIVITY TEST OF 70% ETHANOL EXTRACT GINGER (Zingiber officinale) AGAINST Streptococcus mutans and Escherichia coli BACTERIA

Desi Fitriani Astuti (Tarumanagara Institute, Jakarta)
Kartika Sari (Tarumanagara Institute, Jakarta)



Article Info

Publish Date
25 Jul 2026

Abstract

Ginger (Zingiber officinale) is a herbal plant containing bioactive compounds such as flavonoids, alkaloids, saponins, tannins, and terpenoids that have the potential as natural antibacterials. This study aims to determine the antibacterial activity of 70% ethanol extract of ginger against Streptococcus mutans and Escherichia coli bacteria. The study used a laboratory experimental method with a descriptive quantitative approach. The study population was ginger plants that have the potential to be used as natural antibacterials, while the sample was fresh ginger rhizomes obtained by purposive sampling technique. Extraction was carried out using the accelerated maceration method with 70% ethanol solvent. Antibacterial activity testing was carried out using the disc diffusion method at concentrations of 1%, 3%, 5%, and 10%. The research instruments included a rotary evaporator, incubator, autoclave, micropipette, and caliper. Data were analyzed descriptively using Microsoft Excel. The results showed that ginger extract was able to inhibit the growth of Escherichia coli and Streptococcus mutans bacteria with the highest activity at a concentration of 10%. The conclusion of this study is that 70% ethanol extract of ginger has the potential as a natural antibacterial against Gram-positive and Gram-negative bacteria

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Journal Info

Abbrev

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Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation | ISSN (e): 2986-7754 is a peer-reviewed, open access journal which publishes original research articles and review articles in all areas of nursing and midwifery, research and education. The aim of the journal is to ...