International Journal of Health, Engineering and Technology
Vol. 5 No. 1 (2026): IJHET MAY 2026

Use of 20% Mannitol in Patients with Hemorrhagic Stroke

Ayatullah Malik (a:1:{s:5:"en_US"
s:90:"Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia"
})

Atiqah Luthfiyah (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Desvica Fitriyani Putri (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Ryma Fauzana (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Andini Putri (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Sheren Ariesta (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Raysa Afma (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Rozi Thoyyiba (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Nida Nurul (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)
Selvi Putri Alin (Pharmacist Professional Program, Sekolah Tinggi Ilmu Farmasi Riau (STIFAR RIAU), Indonesia)



Article Info

Publish Date
21 May 2026

Abstract

This case report describes the clinical course, management, and outcome of a 70-year-old male patient diagnosed with hemorrhagic stroke with intracerebral hemorrhage in the right basal ganglia, accompanied by intraventricular hemorrhage and cerebral edema. The patient presented with left-sided weakness, slurred speech, facial asymmetry, and decreased level of consciousness. Comprehensive management included intravenous fluids, osmotic diuretics (mannitol), antifibrinolytics (tranexamic acid), vitamin K, neuroprotective agents (citicoline), antibiotics, and supportive therapies. Despite decompressive craniectomy and intensive care, the patient’s neurological status progressively deteriorated from compos mentis to coma. Monitoring showed unstable vital signs, impaired coagulation parameters, and fluctuating blood glucose levels. No significant drug-related problems or adverse reactions were identified during treatment. However, the severity of brain injury, increased intracranial pressure, and associated complications led to poor clinical outcomes. The patient was declared deceased on January 25, 2026. This case highlights the importance of early intervention, continuous monitoring, and comprehensive management in hemorrhagic stroke patients.

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Journal Info

Abbrev

ijhet

Publisher

Subject

Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Dentistry Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

Description

International Journal of Health, Engineering and Technology (IJHET) is to provide research media and an important reference for the progress and dissemination of research results that support high-level research in the field of Health, Engineering and technology. Original theoretical work and ...