Journal Pharmaceutical Science and Application (JPSA)
Vol. 5 No. 2 (2023): Journal Pharmaceutical Science and Application (JPSA)

OPTIMIZATION OF GUMITIR FLOWER EXTRACT (TAGETES ERECTA L.) SUNSCREEN CREAM: SIMPLEX LATTICE DESIGN METHOD

I Gusti Ngurah Agung Windra Wartana Putra (Pharmacy Department, Bali International University, Denpasar-Indonesia)
I Gusti Ayu Agung Septiari (Pharmacy Department, Bali International University, Denpasar-Indonesia)



Article Info

Publish Date
01 Dec 2023

Abstract

Background: Sunscreen cream is used to protect the skin from the bad effects of sunlight. Making a good sunscreen cream requires paying attention to the composition of the constituent compounds to obtain a standardized cream form quality. Formula optimization is carried out in each cream formulation, including to produce of Gumitir flower extract sunscreen cream. Objective: The aim of this research is to produce an optimum formula for Gumitir flower extract sunscreen cream. Methods: The method used in this research is the Simplex Lattice Design optimization method to find the optimum base between stearate acid cream base and triethanolamine. Results: Optimization results show that variations in stearic acid and triethanolamine cream bases influence the physical properties of viscosity and adhesiveness of sunscreen cream preparations, with stearic acid as the dominant factor influencing viscosity. Conclusion: The conclusion obtained from this research is that the optimum formula for Gumitir flower extract sunscreen cream was obtained with a base composition of 13.5% stearic acid and 2.5% triethanolamine. Keywords: Optimization; Gumitir; Extract; Sunscreen

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Journal Info

Abbrev

jpsa

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

Description

Journal Pharmaceutical Science and Application (JPSA) publishes high-quality original research articles, review articles, and short communications that contribute substantially to the advancement of knowledge in the field of pharmaceutical sciences and their applications. The journal welcomes ...