Childhood cancer requires long-term treatment that can trigger parental stress. The duration of the child’s cancer is assumed to be related to parents’ stress levels due to adaptation processes and prolonged psychological burden. This study aimed to analyze the association between cancer duration and parental stress. A cross-sectional design was conducted using data from a previous study at Dr. Kariadi General Hospital Semarang (August–December 2024). A total of 54 parents were recruited using consecutive sampling. Stress level was measured using the Perceived Stress Scale-10 (PSS-10). Chi-Square was used for analysis. Results showed that most children had cancer <1 year (72.2%), and most parents experienced moderate stress (68.5%). There was a significant association between the duration of child’s cancer and parental stress with p.value 0.001 (p<0.05). It is concluded that higher stress occurs in parents during the early phase of diagnosis. Early psychosocial support is needed.
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