Nursing Pharmacology is considered a challenging subject that requires innovative teaching methods such as Problem Based Learning (PBL) and simulation. PBL fosters active learning, critical thinking, and problem-solving, while simulation enhances understanding through practical experience. This study aimed to evaluate the satisfaction and self-confidence of nursing students in the pharmacology course using the Problem Based Learning (PBL) and Simulation methods. This descriptive quantitative study involved 73 respondents, selected using total sampling. The research instrument was a questionnaire. Data were analyzed using univariate analysis. The results indicated that the majority of students had high satisfaction and self-confidence regarding the PBL and simulation methods in the pharmacology course. Specifically, 68.5% were satisfied, 28.8% were very satisfied, 74.0% felt confident, and 23.3% felt very confident. The PBL and simulation methods in the pharmacology course effectively enhanced student satisfaction and self-confidence, with most respondents reporting positive outcomes.
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