Jurnal Katalisator
Vol. 11 No. 1 (2026): Jurnal Katalisator, Volume 11 No 1 April 2026

EFFECT OF WEST SUMATRAN DADIAH ON BODY WEIGHT AND GLYCEMIA IN HYPERGLYCEMIC RATS

Meri Wulandari (Program Doctoral of Biomedical Science, Faculty of Medicine, Andalas University)
Ety Yerizel (Faculty of Medicine, Andalas University)
Harnavi Harun (Faculty of Medicine, Universitas Andalas)
Efrida (Faculty of Medicine, Universitas Andalas)



Article Info

Publish Date
25 Apr 2026

Abstract

This study was a laboratory-based experimental study using a post-test control group design to evaluate the effect of curd administration on body weight and blood glucose levels in hyperglycemic rat model. Male Wistar rats (Rattus norvegicus) aged 8–10 weeks with body weights of 250–300g were used and randomly divided into four groups: a negative control group without diabetes induction or treatment, a positive control group with diabetes induction without therapy, and two treatment groups receiving curd at different doses, P1 (1.8750 g/250 g body weight) and P2 (3.750 g/250 g body weight). The mean body weight was 277.67 g in the negative control group and 227.50 g in the positive control group. Treatment groups showed increased body weights of 246.83 g in P1 and 262.50 g in P2. Blood glucose levels were 125.56 mg/dL in the negative control group and increased to 487.00 mg/dL in the positive control group, while curd administration reduced levels to 122.17 mg/dL in P1 and 101.83 mg/dL in P2. These results indicate that curd improves body weight and lowers blood glucose in hyperglycemic rats, with greater effects at higher doses, suggesting its potential as a functional food for metabolic and glycemic control.

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Journal Info

Abbrev

katalisator

Publisher

Subject

Agriculture, Biological Sciences & Forestry Chemistry

Description

Jurnal Katalisator (ISSN Online : 2502-0943) is a journal containing scientific articles through a review by peer reviewers in chemistry. Jurnal Katalisator publishes original manuscripts, short review reviews on the branches of chemistry including: organic chemistry, inorganic chemistry, physical ...