Ischaemic stroke is one of the leading causes of disability and mortality worldwide and results not only in physical impairment but also in substantial psychological consequences, particularly depression. This study aimed to analyse changes in depression severity as a neuropsychological manifestation in patients with ischaemic stroke before and after one month of treatment, using the Hamilton Depression Rating Scale (HDRS). A quasi-experimental, one-group pre-test-post-test design without a control group was employed. Depression was assessed at two time points: at the patient's initial visit to the Neurology Outpatient Clinic of Haji General Hospital Medan (pre-test) and one month after treatment (post-test). A total of 50 patients with ischaemic stroke who met the inclusion criteria were enrolled. Data were analysed descriptively to characterise the patients and the distribution of depression severity, and comparative analysis was performed to assess differences in scores before and after treatment. Depression severity decreased significantly after one month of treatment (p < 0.05). These findings indicate that the treatment provided contributed to improvements in the psychological condition of patients with ischaemic stroke.
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