<![CDATA[Acetone has rarely been applied as a single solvent in comparative phytochemical studies of Indonesian medicinal plants, and systematic comparisons of extraction techniques remain limited. This study aimed to evaluate the qualitative phytochemical profiles and potential bioactivity of acetone extracts obtained using maceration and Soxhlet extraction from selected ethnomedicinal plants. The samples included the leaves and fruits of Pereskia bleo, leaves and stems of Gnetum gnemon, leaves of Bouea macrophylla, leaves of Psidium guajava, and the banana inflorescence of Musa paradisiaca. Phytochemical screening revealed that phenolics, steroids, and terpenoids were consistently detected in all samples. Strong flavonoid presence (+++) was observed in several plant parts, particularly P. bleo fruit and G. gnemon. Alkaloids and glycosides were detected only in maceration extracts, reflecting their thermolabile nature. These results demonstrate that acetone effectively profiles secondary metabolites, while extraction methods significantly influence the detection of thermosensitive compounds.]]>
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