AN INVESTIGATION OF THE POTENTIAL ANTI-PROLIFERATIVE AND ANTI-INVASIVE EFFECTS OF NANO-GENISTEIN ON MCF-7 BREAST CANCER CELLS

Nawres Adnan Abdulameer (Polytechnic College - Al-Qadisiyah, Al-Furat Al-Awsat Technical University (ATU), Iraq)
Baydaa Talib Mahdi (Al-Qadisiyah education directorate, Ministry of Education, Iraq)
Shoabith, H. J (Al-Diwaniyah Veterinary Hospital, Veterinary directorate, Ministry of Agriculture, Iraq)
Ibtissem Ben Amara (Laboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of Sfax, Tunisia)

Journal for Technology and Science
Vol. 3 No. 4 (2026): Journal for Technology and Science

Objective: The purpose of this work was to analyze the effects of nanogenistein on the proliferation and metastasis of MCF-7 human breast most cancers cells, as well as to understand the underlying molecular mechanisms. Method: The MCF-7 human breast most cancers mobile panel was supplemented with 10% foetal bovine serum (FBS), 1% penicillin-streptomycin, and 1% American Type Culture Collection (ATCC) non-crucial amino acids. The cells had been incubated at a temperature of 37°C in a managed surroundings with 5% carbon dioxide and were frequently refreshed each 3-4 days. Results: The consequences showed that nanogenistein correctly suppressed the growth of MCF-7 breast cancer cells. The results obtained from the dosage and length of remedy offer critical insights into the efficacy of nanogenistein within the treatment of breast cancer. Novelty: Additional investigation is essential to examine the capability therapeutic use of this nanoformulation in treating breast cancer, as it has shown more suitable anti-proliferative and anti-invasive effects.